Using three AI protein prediction tools, study uncovers new wrinkles in the folding story of 'orphan' proteins
(phys.org)
TLDR; Summary
Study uses AI protein prediction tools to uncover new insights on 'orphan' proteins
Research conducted by Weizmann Institute of Science mentors and Chinese students
Online mentoring led to innovative research on protein evolution
Findings challenge previous beliefs about protein evolution and origin of new proteins
Study explores how 'newly-born' orphan proteins can fold and potentially perform new biological functions
AI algorithms used to predict structures of orphan proteins with novel folds
Research suggests potential for exploiting orphan proteins in various applications
Study findings may change understanding of evolution and origin of life
Research published in journal Proteins: Structure, Function, and Bioinformatics
Authors hope study will inspire further exploration of orphan proteins using AI tools
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