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Using three AI protein prediction tools, study uncovers new wrinkles in the folding story of 'orphan' proteins (phys.org)

TLDR; Summary

  • Study uses AI protein prediction tools to uncover new insights on 'orphan' proteins
  • Research conducted by Weizmann Institute of Science mentors and Chinese students
  • Online mentoring led to innovative research on protein evolution
  • Findings challenge previous beliefs about protein evolution and origin of new proteins
  • Study explores how 'newly-born' orphan proteins can fold and potentially perform new biological functions
  • AI algorithms used to predict structures of orphan proteins with novel folds
  • Research suggests potential for exploiting orphan proteins in various applications
  • Study findings may change understanding of evolution and origin of life
  • Research published in journal Proteins: Structure, Function, and Bioinformatics
  • Authors hope study will inspire further exploration of orphan proteins using AI tools