Unfated.AI Logo

AI helps provide the most complete map of interactions key to bacterial survival (phys.org)

TLDR; Summary

  • Researchers at Autonomous University of Barcelona use AlphaFold2 AI to map bacterial essential interactome
  • 1,402 protein-protein interactions predicted, revealing new details and potential antibiotic targets
  • Bacteria's survival processes involve essential protein complexes
  • AlphaFold2 distinguishes genuine protein interactions from false positives
  • AI model shows excellent predictive power in comparison to experimental data
  • Discovery of new essential protein complexes in processes like DNA replication and cell division
  • Structural details of protein complexes offer insights for antibiotic development